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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db461dbd5380ac9ee66d50a687128b0a2f72719df5c033bdf3061490b835929' 
  AND token = 'OmW5Lumo1jrrk/5m3cPd+esFN2fRMwaFPSe+1AXJ2dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}