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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c961f06b1d87c34904d63b923a7aa46028cbfcfbedb7bf94287d562369decd' 
  AND token = 'k3W0PgUFtxIL3sOh09R5VV64eVuQEPl48N1uSZLcN/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}