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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0c04fb643794d18aaef68655380581c5c65270b309b5897d45d327045dbf04' 
  AND token = '3Gfj6pcR9Oane9Oww1L33dYJxurjpB6tDmYhrJk2adI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}