Sandbox

SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2bdee1d865fe82dd4d6a83ff8a08c049308dd4decf372c8a2b4cf8533a11c6' 
  AND token = 'YyDqCb4kSVYq2DpAjJYQrAyLmbFZaSQAx+UKrQSqY3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}