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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2a3774e4645bd64a4214ea1f049fd8c436964c6b7cdab80c4d4251f75e422d' 
  AND token = 'a16qwm+bmwIDm3YXTAgbKJCDxf8FLo4+7W9CU/qELXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}