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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e116c135b1dd64140826ff1adb12a8b86ba129789e1dffce7ec133407c77a729' 
  AND token = 'NKIG6VVdThpeARjG3QMiyAdZcP+j+2Nv0lkXNnneteY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}