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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49bd987a645d6243ced3b056445c5dc5198c92e0bcae87312c62b08e4c694e1' 
  AND token = '6JXop2ohTeXV+4cB0g+dL6qx+H1Qdqn9dO4mrOYBKW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}