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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb04e9868c75f1d0083f3232f2a45636788d5a100ca5a5d9fd592498072de94' 
  AND token = 'j5UQPgBs4hHaQy6jwI4WJGOIgHpV3IVAwCpVeyaJc3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}