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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc541b57801dce261717b07702a598204e2661ea434b7c2168d1082d95d4432e' 
  AND token = 'UBlF4dbnBpWoP12HFC1Likf2uAec2lSfhgOw4RY/kR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}