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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5694a75e3d83807645690ce34c5018f2d3a6b78e825ec62e37c45f8dc25efa' 
  AND token = 'xK1/oqrkNWIw16fWKSsJpN7qt6p0dJD6zI8bO154UCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}