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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd0841500800494738e82e01d9d253232b3db2fcbafd5b84ddd5c40f08c0782d' 
  AND token = 'aPjMMesu3zl0+MdWeKS4rv0FCs9jJ/quzN0b6Z/fqRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}