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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '815aed34c9de3314c4a8ceb73cc06944e1488fd8e602a5f49542f58275463310' 
  AND token = 'MP0q2+eYxQfURnz64ChVH/E7PTAbyJMh6YNW8jNSJwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}