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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6170a1ad50909d1cbfdf5d10e8b01ebbb34c71c124ea19d7917d3a7a2c376090' 
  AND token = 'cKx3VGbE3J5mN0lClSfGHYsE996dlAVaFG5kGikIn4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}