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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8892274a50e27d55d5c0b97334fb52e27539c7f9ff5ab075560c8807117867' 
  AND token = 'QjCrhAo+bEoKQMeZtiKZJWoX64E0AjRRlX75otjnOhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}