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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '470cf1ae67d611a67a9f140e6ad2b670362474a65d402f063a4d7185ac0a0230' 
  AND token = 'Oq5Pq9B+V+5/E3Mx+MeWxGYn9kHXxTT+gXcR47EML8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}