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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e257bfc4dd071cd9082e2df37b2db3a30445d9d4e9f02b1c0695a9692df88535' 
  AND token = 'dYaGcHJEYFT1hctJexvH39JGkf60pB6ZdxFJvAz7j8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}