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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0557ce837154399d27d3a2c5e2d950f63feefd75417ed1d7248c99030c84e94' 
  AND token = 'p2usNARf67SSx83qp96UeENGV4WGdasq9wvynW2iBqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}