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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2052973f404f62770c3dfcffae3e7d416fc470ecce57c5be4c0bc12f857a83' 
  AND token = 'fGObsWm121ByKyonKVIYAWD7K/JAqA1IwByBlwNH6ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}