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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a4daa065c436cff224cfe6765ef696a07b4a91f7d2d3a6b1a22b4639be951d' 
  AND token = 'Vq9DttTvL0mC2f0cyd/+nibCXWYlXMPjH0G8qTQU78g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}