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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22db2c214842f73c5804e0262e87defd18bca623a4445f5ebd802044c7135660' 
  AND token = 'UtKJ2LnVKelQQ5MlJmeLuTTMVPJXXdUs+H5EBNNNsY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}