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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af9a29b6a6d9f3350a63be67159f07c3d9995915f87623e7171522a667a62595' 
  AND token = '/vjenxsbx933SVztZYugjEMqlaqehqsdvl8Zg4f5OSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}