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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df33ccc4735dce70465a80ed248b107500e5b07a44e94713f79adf89d7f8a4b8' 
  AND token = 'rDewX43kz+ZHjIsitVNFLrAayHMtwY0ecojDeOWMA2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}