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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f34080837eca49ca39d9e56c9c62b7c59aa53108ceef60a5aa155e4fc3eb4d8b' 
  AND token = 'nlPdtT9N7M1BZFc0XpvotgZXmZ13N/R4D36NdHuxNf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}