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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6224b45c2b66ff330f326d80cda86a12dd45fd55a4c7d2a579ce1550562744' 
  AND token = '4Aep/yP46dFkCzChbRueow50FAWbrZNqXbx12w9qk4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}