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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '369181d41a83ef4ed46f802f20310b32a23f4f9efd914cf4db4d8a6ae4235bc5' 
  AND token = 'pk5qt/g0/HsuGcY/l2f0xkndPq1FlW4jTuuUTnA0T4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}