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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12bac034a31bed77f7d5c35852913fb121e78b6dbd7b26923588f21ed59617c' 
  AND token = 'WH3mmhhoTTn9yi5cewGld+3tpmzU79NsgdvYpopNTwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}