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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b049249bc15c5fa75eff62381e160d491f6e3f3d64f700440008f70cc7668171' 
  AND token = '/9+jSiA5ppthqdfDok3xPKS5/XLpKNUMvYC2fi9Y9ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}