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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae52fb0890bd06fcbe64b1a8b4bf4d70feb8be32fce66ed099513961a399bd6' 
  AND token = '33Qf5VZQB1BBJUJx4+5BJ456ibCJ8cXKJzbV+u9nQWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}