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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f0b65435c0090cda3725bb6eae55806a935d1ecb0ba4875d8d2556e3039a90' 
  AND token = 'zOEPlxRadld1CeF/Qv6v6b7+dMT0pO74DkwyoubOZi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}