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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52101ddde6fe9ef2e2aa6655eed30e143bc7d765fce77fec1df5158cd6f0ad5' 
  AND token = 'r5jkE662C/NPDhZhE3utuWm6jI551+vtgFad/YA/3Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}