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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4778c47ec35ed79e73f373e0ec1368386c1eec5d11c32591bd4f2b39bc5375a8' 
  AND token = 'KtAx+VUhivHYACaURd/oYTCMdaLLU55wCp6lmVVX+/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}