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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54554b9a9eff7072d56d084fa82e4f1bdfaf1322c3a03d4d14c3c605a59d3089' 
  AND token = '18xWCYpsJm6HkoaewTTlN2BY6vmcysY6PdD8a6Wqkrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}