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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442c59865c86da53f171ef2ca5bd4e2c14009ed543ed9d470bc2d2923f61455e' 
  AND token = 'zQKVhLwSrVpf6KpAjtbXUzlP/8Dfc51R4xwEHW07Sb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}