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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1c620e7eb522d533f6abd059030c227514b24b004bc1d0a7074837d57b490c' 
  AND token = 'YUcCalCr3M+088R4eI1HVKdRCSgQAZSN2fLfQ2VQvB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}