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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2007d95692f5487b6653506c0e5a4e29de8138f85adbac5891f82db110381a' 
  AND token = 'd5nZyzOM5a+HiO2n0hO6zl+g8O/gfsb10PngBbkVSIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}