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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1b6b8376d7d38d3909861e8ca8a5512b80d3a6b8648d20645e286f2051a811' 
  AND token = 'MA/sBGqH6tbkgsBoIr4MABP9Z5hqfOoeQESFpcJsgl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}