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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7b78e9448e4f75eda2cee4b5afc72c5645393745d0c75e055cc43465d2f5476' 
  AND token = 'Dt70XI8emaA0Q9bmyat6mEhJQTwIisNl2n4FQ7JwXEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}