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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c960dd09bea8cf27a859549431b447ec3c089d0e8ae0de32e9e04942f8a8648e' 
  AND token = 'wP9V9CN+D16YP8l+nIoEexxDT9YEOZkmMQSZ9qwRFwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}