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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d12c8967e4dbe1ab1c7575ad5805a420e0ce9a74b5f37b77b8ac79443d821b1' 
  AND token = 'YQHwkXsoktKlK9aF9quQSxEiIgE15pOcFh1fNaR4Xgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}