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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bac6d986a4f2d7d37148e4d630b2e62bd460fdb71aa0eee2334cbdb51baa64bc' 
  AND token = 'T2xAuIwEvNiZiRxE1GIiKw9Q3uYrmiQIql3N7vvw0Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}