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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e848e9024cb0ddc9873c66fe7f0d5adeb1cc856ff3d6fefacbd2f79aab21c8d' 
  AND token = 'iTnkxlZNdLaib06/aCanC9StynhfcxcohEJORWQHcVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}