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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9193916b33619e190b9f7167e1a0facf6fd0e0a3ca4d867ebdc58856b90791c1' 
  AND token = 'JMpY2aazoKWTd1RXMF+OWfK8sbrDCPBxBemJyIDveEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}