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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949a86dad47e26abf20c6f89c7c4c88c00ad5d493778d24f9fbb89426f2bf9ee' 
  AND token = 'QBGWyx2oBHcxGhoVhDKwIlTin9pD9PTY0t+bos99OnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}