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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e793e64bf3b3bada87da947d7e8e251c05dfb3cd60f250005764b11cdc308358' 
  AND token = 'BIByXx4FG00WV7kcWIYhthf6L+XNYfrW/17YVDOgZx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}