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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8253d3be06772fc072c896de70c93c3d59a2d0e9f9d9d5f85c9c519608d00269' 
  AND token = '0hQt/8/wWT3/CHXypJCUjhgAOvc8mHEW6oHUe7jsIng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}