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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13d2886692ded887d0527e8c1d456099741fe38e04d435cb0c306836a669131d' 
  AND token = 'P25LORk7bUP8VFKFqxNdATg4RcvORQDSI/qtUyrA8sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}