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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452d7192892553c4d7ab1b281d06d515e815291726138672490c1e24760cb5fd' 
  AND token = 'obzYFjkLGQS9m4dbeDOv235Sa9j+cG2KkGmlzp8Wag8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}