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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f74db79eecf20b351558b71e2e7b3f72c2e4ce5abe9c0b7af5ba2a9b9fde8f' 
  AND token = 'V2IN/8vIZvGDRL5liX9MMsBcUOospQjaUv2dkCIXjyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}