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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c1be499ab6bd24330c6debf920bb80255ed63c1eec980f1bb8da8777e7b3b5' 
  AND token = 'TdFVCGYgDElxTIHCZmTYi3gg9INK8lvVqZsp5fbWlSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}