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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106d0f3c4f57663841d4cfaaf6abfc1866663c4a46d091a99a3648ec5ccb099d' 
  AND token = 'SeMUr/h4qej0V8F3NzP5NwbvQgRu4+VSPSW9FY0DX58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}